Screen Quest檢測(cè)試劑盒是一類用于檢測(cè)各種細(xì)胞離子通道以及電位等系列工具，包括膜電位、鈣離子流、多藥物抗性、氯離子以及氯離子通道等方面的指標(biāo)。每種檢測(cè)方案均能提供不同的檢測(cè)方案。

 產(chǎn)品描述：

       Screen Quest檢測(cè)試劑盒是一類用于檢測(cè)各種細(xì)胞離子通道以及電位等系列工具，包括膜電位、鈣離子流、多藥物抗性、氯離子以及氯離子通道等方面的指標(biāo)。每種檢測(cè)方案均能提供不同的檢測(cè)方案。這些高效的檢測(cè)方案為從多角度研究細(xì)胞功能活動(dòng)提供了一種十分有效的方法。細(xì)胞膜內(nèi)外具有不同的膜電壓。膜電位使得細(xì)胞具有類似電池的功能，提供電源操作鑲嵌在膜上多種小分子裝置。在可電刺激激的細(xì)胞中，例如神經(jīng)元，膜電位常用于細(xì)胞不同的區(qū)域信號(hào)傳遞。細(xì)胞膜上某處離子通道的開或者關(guān)，會(huì)誘導(dǎo)產(chǎn)生局部膜電位改變，并引起電流快速傳到膜上的另一處。離子通道已經(jīng)被鑒定為重要藥物發(fā)現(xiàn)的目標(biāo)。

產(chǎn)品特性：

      Screen Quest膜電位檢測(cè)試劑盒 *紅色熒光* 提供了一種快速且均勻檢測(cè)方案，它使用我們*的長(zhǎng)波長(zhǎng)膜電位指示器來檢測(cè)由于離子通道開放或者關(guān)閉而形成的膜電勢(shì)改變。我們?cè)噭┖惺褂眉t色熒光的膜電位指示器在進(jìn)入細(xì)胞后熒光強(qiáng)度增強(qiáng)，并降低來自于篩選復(fù)合物或者細(xì)胞自體熒光的干擾。

產(chǎn)品性能：

     Ex ：635um    

 Em：660um   

產(chǎn)品英文注釋：

       Membrane potential is the difference in voltage between the interior and exterior of a cell. The membrane potential allows a cell to function as a battery, providing power to operate a variety of molecular devices embedded in the membrane. In electrically excitable cells such as neurons, membrane potential is used for transmitting signals between different parts of a cell. Opening or closing of ion channels at one point in the membrane produces a local change in the membrane potential, which causes electric current to flow rapidly to other points in the membrane. Ion channels have been identified as important drug discovery targets. Our Screen Quest Membrane Potential Assay Kit is a homogeneous assay with fast read time. It uses our proprietary long wavelength membrane potential indicator to detect the membrane potential change that is caused by the opening and closing of the ion channels. The red fluorescence of the membrane potential indicator used in the kit has enhanced fluorescence upon entering cells and minimizes the interferences resulted from the screening compounds and/or cellular autofluorescence.

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